Neuraxial anesthesia (NA) appears to be associated with improved overall
survival (OS) in patients undergoing surgery for tumor resection,
particularly in those with colorectal cancer. According to a recent
meta-analysis published in
Oncotarget (2016;7:15262-15273), the authors identified a correlation between the use of NA and reduced risk for cancer recurrence.
The authors found significantly improved OS and reduced cancer
recurrence with NA versus general anesthesia (GA). This finding is among
those that show that anesthetic technique correlates with clinically
important outcomes, including mortality and morbidity. “Specifically, we
found a positive association between neuraxial anesthesia and improved
OS in colorectal cancer (HR [hazard ratio] 0.653; 95% CI 0.430-0.991,
P=0.045, the random-effects model),” they explained.
“Our results suggest that … the use of [NA] has been found to be
associated with improved OS after colorectal cancer, prostate cancer,
gastro-oesophageal cancer, laryngeal and hypopharyngeal cancer, and
ovarian cancer surgery,” the researchers wrote.
More...